Polymyxins as Novel and Safe Mucosal Adjuvants to Induce Humoral Immune Responses in Mice
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چکیده
منابع مشابه
Polymyxins as Novel and Safe Mucosal Adjuvants to Induce Humoral Immune Responses in Mice
There is currently an urgent need to develop safe and effective adjuvants for enhancing vaccine-induced antigen-specific immune responses. We demonstrate here that intranasal immunization with clinically used polypeptide antibiotics, polymyxin B (PMB) and colistin (CL), along with ovalbumin (OVA), increases OVA-specific humoral immune responses in a dose-dependently manner at both mucosal and s...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0061643